Category: depression

My Experiences with Tranylcypromine: The Most Powerful Antidepressant Ever?

Introduction Tranylcypromine (brand name: “Parnate“) is a nonselective and irreversible monoamine oxidase inhibitor (MAOI) used to treat major depressive disorder. See this previous post of mine about MAOIs (written in 2013). Prophetically enough, I wrote: “So my current plan is to first try Moclobemide and then Selegiline. If I don’t die, I’ll start with tranylcypromine and

Continue Reading…

Category: depression

Depression Reveals the Truth: We Live in the Abyss

[Epistemic status: Just poetry, written in a nihilistic mood. Don’t take it so seriously.] When you are in the midst of a deep depression it’s impossible to do anything other than lie in bed and wish to die. Speaking is difficult, writing impossible. So any piece of writing about depression will always be false. False,

Continue Reading…

Category: depression

The Good Drug Guide and the Holy Grail of Chemical Paradise: MAOIs

[Epistemic status: MAOIs probably are the most powerful antidepressants – more evidence for this can be found in an excellent recent post on SlateStarCodex.] I’ve recently read the absolutely excellent classic “The Good Drug Guide” by David Pearce. Pearce is a hardcore transhumanist whose ultimate goal is to abolish all suffering. Even better, he’s not shying away

Continue Reading…